If any team lost theyr best player in the nfl which player loss wud make the biggest difference on the team?

Either Manning in Indy or LT in San Diego.

On a side not if the Bears would lose Grossman, they might win a Superbowl.

P, Manning

He is the Colts!!!!!

Peyton Manning would probably be the obvious choice. He runs that offense like a well-oiled machine.

The first player that comes to mind for me would have to be Peyton Manning for the Colts. Without him on that team, I'm not sure how good of a team they would be. Hands down Manning has to be it!!

I would have to say Manning to the colts

I second that. I think Peyton Manning going down might send the Colts to being a 5-11 team.

However, let's look at it from another direction. Who else thinks that if the Bears lost Rex Grossman, they might win the superbowl?

Peyton Manning

LT

Tony Romo The Cowboys! No other team matters and no other player on any other team matters. Just the AMERICAS TEAM THE DALLAS COWBOYS!!